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Clinical Trials

A clinical trial is a research study in which people can participate. The purpose of a clinical trial is to study the effectiveness of a treatment, medication, experimental drug, or device.

The following is a list of clinical trials with which the Department of Neurology at Dartmouth-Hitchcock Medical Center is currently involved. Talk to your doctor to find out if a clinical trial is right for you.

Epilepsy Clinical Trials
A Pilot Study of the Neural Correlates of Spatial Memory in Epilepsy
An Investigator-initiated, Prospective, Multi-center, Controlled Feasibility Study of Direct Brain Recording and Stimulation for Memory Enhancement
Dartmouth-Hitchcock Epilepsy Center Cortical Stimulation Mapping Registry
Electrophysiological Localization of Human Brain Function
Ep0087: A Multicenter, Open-Label, Randomized, Parallel-Group, Active-Controlled Study To Assess The Efficacy And Safety Of Brivaracetam Administered Intravenously As Treatment For Increased Seizure Activity In An Epilepsy Monitoring Unit Setting
HOBSCOTCH: HOme Based Self-management and COgnitive Training CHanges Lives
Memory, epilepsy and brain stimulation: Oscillatory patterns during real-world navigation and free recall in chronically implanted humans
RNS� System Post-Approval Study in Epilepsy
General Neurology Clinical Trials
Ultrasound Guided Diagnostic Lumbar Puncture in Neurology (UltraGuD LP)
Headache Clinical Trials
A Multicenter, Randomized, Open-Label Extension Study to Evaluate the Long-Term Safety and Tolerability of Oral Ubrogepant in the Acute Treatment of Migraine With or Without Aura
A Non-Invasive Neuromodulation Device for Prevention of Episodic Migraine Headache
Movement Disorders Clinical Trials
A Phase III, Multicenter, Randomized, Double-Blind, Double-Dummy, Active-Controlled Study Comparing the Efficacy and Safety of Gastric Retentive, Controlled Release Accordion PillTM Carbidopa/Levodopa (AP-CD/LD) to Immediate Release CD/LD in Fluctuating Parkinsons Disease Patients
Clinical Manifestations of Inflammasome Activity in Parkinson's Disease
Cross-Sectional ALS Biofluid Biomarker Study
Multiple Sclerosis Clinical Trials
Brain Plasticity/Repair Genes and Neuroimaging in MS
Long-term, prospective, observational, multinational,parallel-cohort study monitoring safety in patients with MS newly started with fingolimod once daily or treated with another approved disease-modifying therapy
Plegridy" (peginterferon �-1a) Real World Effectiveness and Safety Observational Program
Neuromuscular Clinical Trials
A Phase 3, Multi-National, Double-Blind, Randomized, Placebo-Controlled, Stratified, Parallel Group, Study to Evaluate the Safety, Tolerability and Efficacy of Tirasemtiv in Patients with Amyotrophic Lateral Sclerosis (ALS)
A Phase 3, Open-Label Extension Study of Tirasemtiv for Patients with Amyotrophic Lateral Sclerosis (ALS) Who Completed VITALITY-ALS (CY 4031)
A Spatial Analysis of Florida, Ohio, New Hampshire, and Vermont
ALS in Northern NE
Controlled Trial of 3,4 Diaminopyridine in Lambert-Eaton Myasthenic Syndrome (LEMS)
Detection of BMAA and Heavy Toxic Metals in Biospecimen
Northern New England Neurologic Biospecimen Repository
Pilot Study to Evaluate the Efficacy and Safety of Plasma Exchange with Albutein 5% in Patients with Amyotrophic Lateral Sclerosis
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