Research & Clinical Trials
Throughout Dartmouth-Hitchcock and Dartmouth College, scientists and physicians work in partnership with volunteers from the community to develop new treatments at the cutting edge of medical practice.
The Department of Neurology and its faculty actively pursue both basic science and clinical trials research. Actively enrolling clinical trials currently underway in the department are displayed below.
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A clinical trial is a research study in which people can participate. The purpose of a clinical trial is to study the effectiveness of a treatment, medication, experimental drug, or device.
The following is a list of clinical trials with which the Department of Neurology at Dartmouth-Hitchcock Medical Center is currently involved. Talk to your doctor to find out if a clinical trial is right for you.
Epilepsy Clinical Trials
A Pilot Study of the Neural Correlates of Spatial Memory in Epilepsy
An Investigator-initiated, Prospective, Multi-center, Controlled Feasibility Study of Direct Brain Recording and Stimulation for Memory Enhancement
Dartmouth-Hitchcock Epilepsy Center Cortical Stimulation Mapping Registry
Electrophysiological Localization of Human Brain Function
HOBSCOTCH: HOme Based Self-management and COgnitive Training CHanges Lives
Memory, epilepsy and brain stimulation: Oscillatory patterns during real-world navigation and free recall in chronically implanted humans
RNS� System Post-Approval Study in Epilepsy
General Neurology Clinical Trials
Ultrasound Guided Diagnostic Lumbar Puncture in Neurology (UltraGuD LP)
Headache Clinical Trials
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Crossover Study To Evaluate The Efficacy And Safety Of Zolmitriptan Nasal Spray For The Treatment Of Acute Migraine In Subjects Ages 6 To 11 Years, With An Open-Label Extension
A Non-Invasive Neuromodulation Device for Prevention of Episodic Migraine Headache
American Registry for Migraine Research
gammaCore? (non-invasive vagus nerve stimulator) for the acute treatment of pain associated with episodic cluster headaches in adult patients: A Non-Research Registry
Movement Disorders Clinical Trials
A Phase III, Multicenter, Randomized, Double-Blind, Double-Dummy, Active-Controlled Study Comparing the Efficacy and Safety of Gastric Retentive, Controlled Release Accordion PillTM Carbidopa/Levodopa (AP-CD/LD) to Immediate Release CD/LD in Fluctuating Parkinsons Disease Patients
Clinical Manifestations of Inflammasome Activity in Parkinson's Disease
Multiple Sclerosis Clinical Trials
Brain Plasticity/Repair Genes and Neuroimaging in MS
Long-term, prospective, observational, multinational,parallel-cohort study monitoring safety in patients with MS newly started with fingolimod once daily or treated with another approved disease-modifying therapy
Neuromuscular Clinical Trials
A Phase 2, Randomized, Double-blind,Placebo-controlled, 6-Week, Parallel-design Study of the Efficacy and Safety of VX-150 in Treating Subjects With Pain Caused by Small Fiber Neuropathy
A Pilot study to determine the brain connectivity disruptions in patients with Amyotrophic Lateral Sclerosis
A Spatial Analysis of Florida, Ohio, New Hampshire, and Vermont
Controlled Trial of 3,4 Diaminopyridine in Lambert-Eaton Myasthenic Syndrome (LEMS)
Cross-Sectional ALS Biofluid Biomarker Study
Detection of BMAA and Heavy Toxic Metals in Biospecimen
Northern New England Neurologic Biospecimen Repository
Pilot Study to Evaluate the Efficacy and Safety of Plasma Exchange with Albutein 5% in Patients with Amyotrophic Lateral Sclerosis