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Research & Clinical Trials

The Department of Psychiatry is committed to the advancement of the practice of psychiatry with a focused emphasis on new research aimed at further understanding of psychiatric disorders and their optimal treatment. Research projects span animal studies, neuroimaging, innovative effectiveness trials and health service studies.

We also conduct clinical trials to study the effectiveness of a treatment, medication, experimental drug, or device. See our list of active clinical trials

Members of the Department work within the Neuroscience Center at Dartmouth, a site of cutting edge translational neuroscience research, as well as within the Norris Cotton Cancer Center, the Dartmouth SYNERGY Clinical and Translational Research Institute, and the Dartmouth Institute of Health Policy and Clinical Practice.

Currently, thirty members of the Department serve as Principal Investigators of investigator-initiated externally funded research grants from federal agencies, state agencies, foundations and industry. The disorders under study include schizophrenia (and other serious mental illness), substance use, traumatic brain injury, post-traumatic stress disorder, ADHD, depression, Alzheimer’s Disease, autism and multiple sclerosis.

The research programs involve neuropsychopharmacology, study of endophenotypes, neuroimaging and neurogenetics, psychiatric rehabilitation, and outcomes studies.

Major research groups include the National Center for PTSD, the Dartmouth Brain Imaging Lab, the Center for Technology and Behavioral Health, and the Psychopharmacology Research Group.

Other areas of research include:

  • Neuropsychiatry: Disorders under study include traumatic brain injury (TBI), multiple sclerosis (MS), psychiatric disorders, as well as pediatric neuropsychology.
  • Post-traumatic stress disorder (PTSD): A major area of research interest is trauma and trauma-related disorders. The National Center for PTSD Executive Division is focused primarily on clinical trials of PTSD treatments and patient decision aids, educational product evaluation, and assessing models of care and improving evidence-based practice. Dartmouth Trauma Interventions Research Center and the Center for Technology and Behavioral Health are also conducting research in this area.
  • Patient-oriented cancer survivorship: Research is exploring the physical, psychological, functional, and social effects of cancer.
  • Mood disorders: Research is being conducted in major depressive disorders, medication-resistant depression in patients with temporal lobe epilepsy, and treatment-resistant depression.

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