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Endometrial Biopsy

In this procedure, your doctor or nurse will take a tissue sample from the endometrium (the inside lining of the uterus) and have it examined.

Why do this test?

  • The test is useful for determining the cause of abnormal bleeding, bleeding after menopause, or bleeding associated with taking hormone replacement medications.
  • It can be used to screen for endometrial cancer.
  • It may be able to help determine why some women have been unable to get pregnant.

The procedure

You will lie on an examination table with your feet in the stirrups, and your doctor or nurse will use a speculum to make the cervix more visible. You may choose to have spray anesthesia.

Your doctor or nurse will clean the cervix with antiseptic, then steady it with an instrument called a tenaculum. He or she will pass a small plastic tube into the uterus, and use gentle suction to take a small sample of the lining. A pathologist will examine it for abnormalities.

After the test

Slight bleeding is common after this procedure, and there is a small chance of infection.

Abnormal results

An abnormal result may indicate uterine fibroids or polyps, endometrial cancer, or other conditions.

If you are having the test because of pregnancy issues, it should indicate whether your uterine lining is suitable for implantation of a fertilized egg.

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