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Connective Tissue Disease

Our Rheumatology team treats a range of connective tissue diseases, which may include conditions listed below. The links provided below refer to topics on our Dartmouth-Hitchcock Healthwise® Health Encyclopedia website:

  • Antiphospholipid antibody syndrome: A rare disorder, which causes recurrent blood clots. It usually occurs in women before age 45 and is sometimes associated with lupus or other autoimmune disorders.
  • Dermatomyositis: Connective-tissue disease that is characterized by inflammation of the muscles and the skin.
  • Dupuytren's Contracture: A painless thickening and tightening of tissue beneath the skin on the palm of the hand and fingers. Progressive contracture may result in deformity and loss of function of the hand.
  • Marfan Syndrome: An inheritable disorder of connective tissue (the tissue that strengthens the body's structures) and may affect the skeletal system, cardiovascular system, eyes, and skin.
  • Mixed Connective Tissue Disease: A rare disorder involving multiple diseases that include systemic lupus erythematosus (SLE), systemic sclerosis, and polymyositis.
  • Myalgia/Myositis: An inflammation or swelling of the voluntary (skeletal) muscles, often caused by injury, infection, or autoimmune disease.
  • Polymyositis: An inflammatory disease that causes significant muscle weakness.
  • Raynaud's Phenomenon: A condition in which exposure to the cold or strong emotions trigger blood vessel spasms that result in interruption of blood flow to the fingers, toes, ears, and nose.
  • Systemic Sclerosis: Also known as scleroderma, this condition can cause hardening of the skin, digestive problems, joint stiffness, and pain.
  • Sjogren Syndrome: A systemic inflammatory disorder characterized by dry mouth, decreased tearing, and other dry mucous membranes. It is often associated with autoimmune rheumatic disorders.
  • Tendinitis: Inflammation, irritation, and swelling of a tendon, which is the fibrous structure that joins muscle to bone.
  • Tietze disease: A rare inflammatory disorder with symptoms including chest pain and Costochondritis, or an inflammation of a rib or the cartilage connecting a rib.
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