The Transfusion Medicine Research Center provides a full range of clinical laboratory testing from one convenient location. These processes include extracting proteins for study, preserving and testing platelets, and collecting plasma for research purposes. The complete list of current testing available includes, but is not limited to, the following:
- 2-3 DPG
- Acid protein extractions
- Blood gas
- Blood product sterility testing
- Glycerolize/deglycerolize red blood cells
- Platelet aggregation
- Platelet and RBC morphology
- Platelet and RBC recovery and survival
- Platelet cryo-preservation
- Platelet hypotonic shock
- Platelet extent of shape change
- Residual white blood cells
- Sample processing
- Supernatant Hemoglobin
- Whole blood, platelet, red blood cells, white blood cells, and plasma collections (manual and automated)
The Transfusion Medicine Research Center has participated in numerous published studies. Here is a selection:
"Removal of Yersinia Enterocolitica from AS-1 red cells." DH Buchholz, JP AuBuchon, EL Snyder, R Kandler, S Edberg, V Piscitelli, C Pickard, P Napychank. Transfusion 1992; 32:667-72.
"A Randomized, Controlled, 2-Period Crossover Study of Recovery and Lifespan of Radiolabeled Autologous 35-Day-Old Red Blood Cells Prepared With a Modified S-303 Treatment for Pathogen Inactivation." Cancelas JA, Dumont L, Herschel L, Rugg N, Garratty G, Arndt P, Propst M, Corash L, Sundin D, AuBuchon J. Vox Sanguinis 2008;95(Suppl.1):1-71.
"Red Blood Cell Metabolic Responses to refrigerated storage, rejuvenation, and frozen storage." D’Alessandro A, Gray AD, Szczepiorkowski ZM, Hansen K, Herschel LH, Dumont LJ. Transfusion. 2017 Mar 10. doi: 10.1111/trf:14034 PMID: 28295356\
"Automated Collection of Double Red Blood Cell Units with a Variable-Volume Separation Chamber." JP AuBuchon,LJ Dumont, L Herschel, J Roger, RL Beddard, HL Taylor, PH Whitley, SL Sawyer, S Graminske, K Martinson,R Dora, S Heldke, J Adamson, LE Rose. Transfusion 2008;48:147-152.
"Red Blood Cell Storage in Additive Solution-7 preserves energy and redox metabolism: a metabolomics approach." D’Alessandro A, Nemkov T, Hansen KC, Szczepiorkowski ZM, Dumont LJ. Transfusion 2015
"The Bioequivalence of Frozen Plasma Prepared from Whole Blood held overnight at room temperature compared to fresh-frozen plasma prepared within eight hours of collection." Dumont LJ, Cancelas JA, Maes LA, Rugg N, Whitley P, Herschel L, Siegel AH, Szczepiorkowski ZM, Hess JR, Zia M. Transfusion. 2014 Sep 19. doi: 10.1111/trf.12864. PMID: 25233805.
"Evaluation of a New Prestorage Leukoreduction Filter for Red Blood Cells." JP AuBuchon, MD Elfath, MA Popovsky, RR Stromberg, C Pickard, L Herschel, P Whitley, D McNeil, N Arnold, JL O'Connor. Vox Sang 1997;72:101-6.
- Independent publication
"Viability and In Vitro Properties of Gamma-Irradiated AS-1 Red Blood Cells." G Moroff, S Holme, JP AuBuchon, A Heaton, J Sweeney, LI Friedman. Transfusion 1999;39:128-34.
The Transfusion Medicine Research Center has offered research assistance in additional studies.
- Advanced Preservation Technologies