The Transfusion Medicine Research Center is one of only four labs of its type in the United States.
Proof-of-concept and pre-FDA licensure Phase I/II clinical trials for transfusion medicine-related products and processes
The center offers an experienced team qualified to participate in proof-of-concept and pre-FDA licensure Phase I/II clinical trials. This may be for, but not limited to:
- Frozen storage of platelets and red cells
- In vitro studies for bacterial contamination detection technology
- Instrument evaluation for whole blood, red cell, platelet and plasma collection
- New anticoagulants or additive solutions for platelets and red cells
- New plastics for platelet and red cell storage bags
- Novel storage conditions for platelets and red cells
- Pathogen reduction technology for platelets and red cells
Radioactive recovery and survival studies
Radioactive recovery and survival studies are a particular area of expertise for the Transfusion Medicine Research Center. The center has more than 25 years of experience with in vivo trials for platelets and red cells. It has a stable subject base with historical recovery and survival studies for numerous types of red cell and platelet additive solutions and storage conditions.
The center has the capability to function as a reference laboratory for other research laboratories. Offerings include:
- Mock audits
- Red cell metabolism (ATP/DPG)
- SOP development
- Storage lesion (potassium/supernatant hemoglobin/microvesicle isolation)
- Validation development and implementation
The center performs numerous other tasks, including evaluation of instrumentation for collection and storage and quality assurance assistance within the Department of Pathology and Laboratory Medicine.